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Bone Grafts and Substitutes Market: Obesity and diabetes to increase the risk of degenerative joint diseases

Rise in incidences of musculoskeletal conditions, technological advancements in medical devices, and development of biocompatible synthetic bone grafts fuel the growth of the global bone grafts and substitutes market. On the other hand, high cost of surgeries and ethical issues related with bone grafting procedures impede the growth to some extent. However, emerging market opportunities are expected to be beneficial for the market.


The global bone grafts and substitutes market was valued at $2.65 billion in 2020, and is projected to reach $3.36 billion by 2028, registering a CAGR of 4.3% from 2021 to 2028. Bone grafting is a surgical procedure that helps repair fractured, injured, and missing bones in the patient’s body.

COVID-19 scenario-

  • The outbreak of COVID-19 has made the key players in the industry face issues in regards to the availability of human resources for manufacturing bone grafts & substitutes at production facilities, which in turn has impacted the market negatively.
  • However, government bodies in several countries have come up with relaxed norms and the market is anticipated to revive soon.

Rapid development of novel bone grafts materials such as biocompatible synthetic bone grafts and rise in prevalence of bone and joint disorders are the major factors driving the growth of the global bone grafts and substitutes market. Moreover, surge in the number of patients suffering from rheumatoid arthritis, osteoarthritis, and other joint disorders have supplemented the market growth. However, high cost of surgeries and several ethical issues associated with bone grafting procedures have hampered the market development. On the contrary, increasing inclination of key market players toward R&D activities and surge in demand for orthopedic procedures among geriatric population would provide lucrative opportunities for the market leaders in the coming years.

Key market players

The leading companies in the global bone grafts and substitutes market include Medtronic plc, DePuySynthes, Wright Medical Group N.V., Xtant Medical Holdings, Inc. (Bacterin), Baxter International Inc., Stryker Corporation, Integra Lifesciences Holdings Corporation, Zimmer Biomet Holdings, Inc., Arthrex, Inc., and Musculoskeletal Transplant Foundation (MTF).

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quote The increase in number of patients suffering from bone-related diseases, and surge in elderly population further fuels the growth of the bone grafts and substitutes market quote

Onkar Sumant


Manager, Healthcare at Allied Market Research

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